Associate Medical Director, Pathology

Zoek Pin Irvington, NJ

Competitive

Permanent (Full time)

Posted 39 days ago

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine?

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

OBJECTIVES/PURPOSE

This role provides a unique opportunity for an anatomic/molecular MD pathologist to utilize their distinct expertise to help drive the development of our next-generation of immunomodulatory therapies in oncology, from early discovery into clinical development. This will be achieved by:

  • Serving as a key member of an early translational oncology group that is dedicated to identifying biomarkers that provide a continuum between preclinical drug discovery and early clinical trial testing across multiple drug programs.
  • Assisting in the development of molecular pathology capabilities that combine tissue-based technologies with innovative human tissue model systems for biomarker discovery and patient stratification strategy development.
  • Establishing laboratory best practices and overseeing tissue-based RUO assay validation for clinical trial use.
  • Providing clinical trial support across our oncology programs as needed.

SCOPE

This is a highly collaborative role that involves cross-functional collaborations across immune-oncology programs and the clinical development teams at Takeda Oncology in Cambridge, MA. As a member of the Integrated Translational Technologies Laboratory, this role will leverage cell immunophenotyping capabilities for cross-program support and larger integration across drug development teams. The overall goal will be to assimilate discovery findings to rationally inform the development of clinical biomarker and patient stratification strategies while contributing to proof-of-concept and mechanistic evaluation of assets in the pre-clinical and clinical space.

*ACCOUNTABILITIES***Innovative Technology Development:**

  • Directly embed within a small team of scientists with expertise in IHC, RNA ISH, multiplexed immunofluorescence and image analysis to develop and deliver immunophenotyping capabilities that can identify drug-mediated changes in the tumor-immune environment. Work with technology partners to assess innovative technologies that can expand translational biomarker discovery.
  • Engage across our preclinical, translational, and early clinical teams to implement immunophenotype testing and image analysis to directly support go-no-go decision making and preclinical to early-clinical drug development efforts.
  • Contribute to developing preclinical laboratory best practices to assure high-quality testing and data analysis.
  • Cross-Program Collaborations To Drive Translation:
  • Work closely with our molecular genomics group, flow cytometry group, and external collaborators to combine cross-platform data for driving early preclinical development of promising oncology assets.
  • Prepare and effectively communicate high-level overview of scientific testing results and analysis to project teams.
  • Provide medical/scientific expertise, literature review, and overarching data review for the completion of regulatory documents, protocols, reports, and publications where necessary.
  • Human Biobank Support:
  • Contribute to the development of academic and provider partnerships to gain access to clinically-relevant patient specimens and longitudinal data required to successfully drive translational investigations across preclinical programs.
  • Participate in quality assessments of samples entering the biobank, including H&E slide review and diagnosis confirmation.

DIMENSIONS AND ASPECTS

Technical/Functional (Line) Expertise

  • Applies pathology/molecular diagnostics expertise to the successful development and implementation of tissue-based testing platforms and assays.
  • Serves as the recognized pathology expert on an aspect of a program.
  • Demonstrates effective project management skills.
  • Develops and oversees application of pathology insights into the translational strategy of project teams and will manage the work of others directly or in a matrixed structure.
  • Independently manages workload and expectations.
  • Scientifically independent.
  • Provides information to group to influence direction, departmental goals and/or business.
  • Collaborates with others, and acts as scientific resource for an aspect of a program.
  • Participates in external interactions and collaborations.
  • Receives high level instructions on work; determines methods on new assignments; clear scientific independence.
  • May have direct reports.

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • MD, PhD is preferred (minimally an MD or internationally recognized equivalent degree)
  • Board certification in Anatomic Pathology or Anatomic and Clinical Pathology
  • Excellent oral and written communication skills, including writing, reviewing and editing scientific documents
  • Superior interpersonal skills, diplomacy and positive influencing abilities
  • Ability to work and drive decision-making within a multi-disciplinary, multi-regional, matrix teams
  • Knowledge of immune cell phenotyping markers preferred.

TRAVEL REQUIREMENTS:

  • Ability to drive to or fly to various meetings or R&D sites including overnight trips
  • Some international travel may be required.
  • This role is considered a hybrid position and you must be able to work onsite in Cambridge, MA on average 2-3 days per week.

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Effective November 1, 2021, absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. As of the same date, absent an approved religious or medical reason, US field-based employees, employees must be fully vaccinated in order to continue in their current roles. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. Candidates are encouraged to speak with their recruiter to seek further information on the applicable guidelines for the Business Unit/Function for which they have applied.

Empowering Our People to Shine

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No Phone Calls or Recruiters Please.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

LI-JT1

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

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